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First issue offprint of their groundbreaking paper presenting their DNA model for the first time with signatures by four of the scientists, including Crick and Wilkins

J. D. Watson and F. D. H. Crick, et. al. "Molecular Structure of Nucleic Acids," an offprint from Nature, Vol. 171, p. 737, April 25, 1953. [London]: Fisher, Knight & Co., Ltd., [1953]. 8vo. [14] pages made up of 6 conjugate leaves and one half-leaf, the single leaf tipped onto the preceding leaf as issued. With two figures, including the double helix, and two photographic illustrations. Self-wrappers, stapled as issued. Comprising three papers, all issued under the heading "Molecular Structure of Nucleic Acids": "A Structure for Deoxyribose Nucleic Acid" by J. D. Watson and F. H. C. Crick; "Molecular Structure of Deoxypentose Nucleic Acids" by M. H. F. Wilkins, A. R. Stokes, and H. R. Wilson; and "Molecular Configuration in Sodium Thymonucleate" by Rosalind E. Franklin and R. G. Gosling.

FIRST OFFPRINT EDITION, FIRST ISSUE, preceding the single-leaf, double-column offprint. Signed by four of the seven scientists whose work was included. Signers include: "M H F Wilkins" and "Francis Crick," signing next to the title of the first paper; "H. R. Wilson," signing next to his name following the second paper; and "R. G. Gosling," signing next to his name following the third paper.

Although Watson and Crick had previously discussed their model informally within scientific circles, their paper in the April 1953 issue of Nature was the first public announcement of their double-helix model. Though the exact number of offprints printed is unknown, the number was undoubtedly small; according to Dr. Haskell F. Norman, who, like most collectors today, preferred the offprint, "It is the offprint, issued in limited quantities of twenty-five to fifty, which authors often sent to friends, frequently with their inscriptions."

Watson, Crick, and Wilkins shared the Nobel Prize in Physiology or Medicine in 1962 for the discoveries first published in these papers.

Condition: Lightly and evenly toned; slight wrinkling at lower right corner; else, fine.

References: Dibner, Heralds of Science, 200; Garrison-Morton 256.3; Haskell F. Norman, M.D., "One Hundred Books Famous in Medicine: Notes on the Exhibition" in Gazette of the Grolier Club, Number 46, 1994, pp. 9-19; Heirs of Hippocrates 2342.


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